ADVERTISEMENT
  • Home
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms of Service
  • Editorial Guidelines
Friday, July 1, 2022
Life Care News
  • Home
  • Business
    • BusinessWire
    • GlobeNewswire
    • Banking
  • News

    APL Apollo Launches Colour Coated Coils and Sheets First Time in India

    Investment in Real Estate Sector Upswing in 2022

    Anand and Naik to Chart New Course Following JV Formalisation

    Shikshan Parishad 2022 : Honours Outstanding Education Institutes at ABP Asmita

    NimbusPost Introduces New Service to Simplify Cross-border Shipping – NimbusGlobal

    MYRE Capital Receives Huge Demand for Commercial Property in Bangalore; Launches a New Floor in the Same Building to Meet Demand

    Astrotalk Comes on Board as the Co-presenting Sponsor for Swayamwar: Mika di Vohti on Disney+ Hotstar

    Leading Co-living Player Housr Acquires StayAbode, Enters Bangalore Market

    CM Naveen Patnaik Expressed the Need for Immediate Reporting of Crimes Against Women at News18 Network and Truecaller’s #CallItOut Odisha Townhall

    The Maestro Felicitated at The Masterpiece, Phoenix Kessaku

    Trending Tags

    • Donald Trump
    • Future of News
    • Climate Change
    • Market Stories
    • Election Results
    • Flat Earth
    • Startups
    • Feature News
    • Energy
    • Real Estate
    • Environment
    • Uncategorized
  • Tech

    MTAR Technologies Limited Receives Orders of USD 22.12 Million in Clean Energy

    Rohde & Schwarz Offers New Ultra-Wideband Test Solution Validated for FiRa Consortium PHY Conformance

    Power League Gaming Names Langoor as New Digital Transformation Agency Partner

    Rohde & Schwarz extends the R&S ZNB vector network analyzer family maximum frequency to 43.5 GHz

    Rohde & Schwarz enhances R&S RTP high-performance oscilloscope

    Automating Battery Production for eMobility Applications

    ecom instruments at the Hannover Messe 2022: Smart Devices for the Digitalization of Hazardous Areas

    The Fischer family has created the technology group Conextivity to extend its expertise and innovation

    RAMINFO growth momentum continues in Q4 FY22 with 366% YoY rise in Net Profit

    Device Data: Do-It-Yourself Is History

    Trending Tags

    • Flat Earth
    • Sillicon Valley
    • Mr. Robot
    • MotoGP 2017
    • Golden Globes
    • Future of News
  • Entertainment

    Social network Zorro rebrands as Hood ahead of its US launch

    MARATHON DU MONT-BLANC, MORE THAN 2,000 RUNNERS ON THE SLOPES OF EUROPE’S HIGHEST PEAK

    Strong Studios and The Cartel Announce Start of Production

    Hilarious Dialogues From AndTV Shows To Tickle Your Funny Bones!

    Ribbon Wins TIA QuEST Forum Sustainability Award for Excellence in Network Equipment Sustainability

    Petal Search celebrates incredible growth on its 2nd Anniversary

    Champions Crowned at YMCA National Gymnastics Championship

    Startek® Recognized Among India’s Best Companies to Work For 2022 by Great Place to Work® Institute

    AORUS ELITE is the best go-to motherboard for upgrade

    Curiosity Ink Media Goes Ape for Animated Family Comedy

    • Lifestyle

      International and Domestic manufacturers and exporters from 15 countries to showcase latest in apparel, textile and fashion industry innovations at ASW 2022

      Asian Paints has Launched their 2022 Collection in Home Decor

      California Pistachio Brings to Life

      It’s Rally Time for Houston’s Teachers

      Pearl Green Clubs and Resorts Limited to Raise Rs. 1171.80/- Lakhs through SME IPO, Issue Opens on June 27, 2022

      One in Two Women Cite Yoga to be their Panacea to Beat the Blues

      Chargebee Earns 2022 US Great Place to Work Certification™

      Neutrogena Uncomplicates Skincare to Support Women in their Journey to Get Beautiful Skin

      India-based Global Performance Marketing Giant Adsparkx Organises Beer Yoga Session for its Employees

      Toggled Unveils New Fixture Controller for Network Lighting Control Management at LightFair 2022

      Trending Tags

      • Golden Globes
      • Mr. Robot
      • MotoGP 2017
      • Climate Change
      • Flat Earth
    • Fashion
    • Travel
  • Health
    • Food
  • Education
    • Books
  • Technology
  • Automobile
  • Sports
    • Olympic
No Result
View All Result
Life Care News
  • Home
  • Business
    • BusinessWire
    • GlobeNewswire
    • Banking
  • News

    APL Apollo Launches Colour Coated Coils and Sheets First Time in India

    Investment in Real Estate Sector Upswing in 2022

    Anand and Naik to Chart New Course Following JV Formalisation

    Shikshan Parishad 2022 : Honours Outstanding Education Institutes at ABP Asmita

    NimbusPost Introduces New Service to Simplify Cross-border Shipping – NimbusGlobal

    MYRE Capital Receives Huge Demand for Commercial Property in Bangalore; Launches a New Floor in the Same Building to Meet Demand

    Astrotalk Comes on Board as the Co-presenting Sponsor for Swayamwar: Mika di Vohti on Disney+ Hotstar

    Leading Co-living Player Housr Acquires StayAbode, Enters Bangalore Market

    CM Naveen Patnaik Expressed the Need for Immediate Reporting of Crimes Against Women at News18 Network and Truecaller’s #CallItOut Odisha Townhall

    The Maestro Felicitated at The Masterpiece, Phoenix Kessaku

    Trending Tags

    • Donald Trump
    • Future of News
    • Climate Change
    • Market Stories
    • Election Results
    • Flat Earth
    • Startups
    • Feature News
    • Energy
    • Real Estate
    • Environment
    • Uncategorized
  • Tech

    MTAR Technologies Limited Receives Orders of USD 22.12 Million in Clean Energy

    Rohde & Schwarz Offers New Ultra-Wideband Test Solution Validated for FiRa Consortium PHY Conformance

    Power League Gaming Names Langoor as New Digital Transformation Agency Partner

    Rohde & Schwarz extends the R&S ZNB vector network analyzer family maximum frequency to 43.5 GHz

    Rohde & Schwarz enhances R&S RTP high-performance oscilloscope

    Automating Battery Production for eMobility Applications

    ecom instruments at the Hannover Messe 2022: Smart Devices for the Digitalization of Hazardous Areas

    The Fischer family has created the technology group Conextivity to extend its expertise and innovation

    RAMINFO growth momentum continues in Q4 FY22 with 366% YoY rise in Net Profit

    Device Data: Do-It-Yourself Is History

    Trending Tags

    • Flat Earth
    • Sillicon Valley
    • Mr. Robot
    • MotoGP 2017
    • Golden Globes
    • Future of News
  • Entertainment

    Social network Zorro rebrands as Hood ahead of its US launch

    MARATHON DU MONT-BLANC, MORE THAN 2,000 RUNNERS ON THE SLOPES OF EUROPE’S HIGHEST PEAK

    Strong Studios and The Cartel Announce Start of Production

    Hilarious Dialogues From AndTV Shows To Tickle Your Funny Bones!

    Ribbon Wins TIA QuEST Forum Sustainability Award for Excellence in Network Equipment Sustainability

    Petal Search celebrates incredible growth on its 2nd Anniversary

    Champions Crowned at YMCA National Gymnastics Championship

    Startek® Recognized Among India’s Best Companies to Work For 2022 by Great Place to Work® Institute

    AORUS ELITE is the best go-to motherboard for upgrade

    Curiosity Ink Media Goes Ape for Animated Family Comedy

    • Lifestyle

      International and Domestic manufacturers and exporters from 15 countries to showcase latest in apparel, textile and fashion industry innovations at ASW 2022

      Asian Paints has Launched their 2022 Collection in Home Decor

      California Pistachio Brings to Life

      It’s Rally Time for Houston’s Teachers

      Pearl Green Clubs and Resorts Limited to Raise Rs. 1171.80/- Lakhs through SME IPO, Issue Opens on June 27, 2022

      One in Two Women Cite Yoga to be their Panacea to Beat the Blues

      Chargebee Earns 2022 US Great Place to Work Certification™

      Neutrogena Uncomplicates Skincare to Support Women in their Journey to Get Beautiful Skin

      India-based Global Performance Marketing Giant Adsparkx Organises Beer Yoga Session for its Employees

      Toggled Unveils New Fixture Controller for Network Lighting Control Management at LightFair 2022

      Trending Tags

      • Golden Globes
      • Mr. Robot
      • MotoGP 2017
      • Climate Change
      • Flat Earth
    • Fashion
    • Travel
  • Health
    • Food
  • Education
    • Books
  • Technology
  • Automobile
  • Sports
    • Olympic
No Result
View All Result
Life Care News
No Result
View All Result
ADVERTISEMENT
Home BusinessWire

Vertex Announces Reimbursement Agreement in Australia for TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) for Patients With Cystic Fibrosis Ages 12 Years and Older With at Least One F508del Mutation in the CFTR Gene

by business wire news
27/03/2022
in BusinessWire
250 2
0
491
SHARES
1.4k
VIEWS
Share on FacebookShare on TwitterShare on WhatsApp
ADVERTISEMENT

– With this reimbursement agreement in place, more than 2,200 people with CF will have PBS-funded access to TRIKAFTA®, including more than 700 who will now have access to a CFTR modulator therapy for the first time –

LONDON–(BUSINESS WIRE)–Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced that as of 1 April 2022, TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) will be reimbursed on the Australian Pharmaceutical Benefits Scheme (PBS) for the treatment of cystic fibrosis (CF) in people ages 12 years and older who have at least one F508del mutation in the CFTR gene, the most common CF-causing mutation worldwide.

“Today’s announcement is a significant milestone in ensuring Australians living with CF receive timely and sustainable access to TRIKAFTA,” said Ludovic Fenaux, Senior Vice President, Vertex International. “This is the fourth treatment we have brought to Australians over the last eight years, working tirelessly alongside the CF patient and clinical communities. We thank the Australian Government for recognizing the significant need for TRIKAFTA and the value it brings.”

TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) was approved by the Australian Therapeutic Goods Administration (TGA) in March 2021 based on the results of four global Phase 3 clinical trials, which included multiple Australian trial sites and patients.

ADVERTISEMENT

CF is a rare, life-shortening, genetic disease affecting approximately 3,500 people in Australia. It is caused by a defective and/or missing CFTR protein, resulting from mutations in the CFTR gene. Up to 90 percent of people living with CF have at least one F508del mutation.

“As a genetic disease, cystic fibrosis is a prime candidate for precision medicine. Now, with PBS listing of TRIKAFTA, eligible Australians living with CF ages 12 years and older can broadly access a therapy that treats the underlying cause of their disease. Clinicians across Australia will be excited about this most welcome news,” said Professor John Wilson AM, Head, Cystic Fibrosis Service, Alfred Health Australia.

Australia now joins the list of 30 countries where the triple combination therapy is approved and reimbursed including Denmark, Finland, France, Germany, Italy, Ireland, Israel, Poland, Spain, Switzerland and the countries within the U.K.

About Cystic Fibrosis

Cystic fibrosis (CF) is a rare, life-shortening genetic disease affecting more than 83,000 people globally. CF is a progressive, multi-organ disease that affects the lungs, liver, pancreas, GI tract, sinuses, sweat glands and reproductive tract. CF is caused by a defective and/or missing CFTR protein resulting from certain mutations in the CFTR gene. Children must inherit two defective CFTR genes — one from each parent — to have CF, and these mutations can be identified by a genetic test. While there are many different types of CFTR mutations that can cause the disease, the vast majority of people with CF have at least one F508del mutation. CFTR mutations lead to CF by causing the CFTR protein to be defective or by leading to a shortage or absence of CFTR protein at the cell surface. The defective function and/or absence of CFTR protein results in poor flow of salt and water into and out of the cells in a number of organs. In the lungs, this leads to the buildup of abnormally thick, sticky mucus, chronic lung infections and progressive lung damage that eventually leads to death for many patients. The median age of death is in the early 30s.

About TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor)

ADVERTISEMENT

In people with certain types of mutations in the CFTR gene, the CFTR protein is not processed or folded normally within the cell, and this can prevent the CFTR protein from reaching the cell surface and functioning properly. TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) is an oral medicine designed to increase the quantity and function of the CFTR protein at the cell surface. Elexacaftor and tezacaftor work together to increase the amount of mature protein at the cell surface by binding to different sites on the CFTR protein. Ivacaftor, which is known as a CFTR potentiator, is designed to facilitate the ability of CFTR proteins to transport salt and water across the cell membrane. The combined actions of elexacaftor, tezacaftor and ivacaftor help hydrate and clear mucus from the airways.

For complete product information, please see the Summary of Product Characteristics that can be found on https://www.tga.gov.au/apm-summary/trikafta.

About Vertex

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases. The company has multiple approved medicines that treat the underlying cause of cystic fibrosis (CF) — a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF. Beyond CF, Vertex has a robust pipeline of investigational small molecule, cell and genetic therapies in other serious diseases where it has deep insight into causal human biology, including sickle cell disease, beta thalassemia, APOL1-mediated kidney disease, pain, type 1 diabetes, alpha-1 antitrypsin deficiency and Duchenne muscular dystrophy.

Founded in 1989 in Cambridge, Mass., Vertex’s global headquarters is now located in Boston’s Innovation District and its international headquarters is in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America. Vertex is consistently recognized as one of the industry’s top places to work, including 12 consecutive years on Science magazine’s Top Employers list and one of the 2021 Seramount (formerly Working Mother Media) 100 Best Companies. For company updates and to learn more about Vertex’s history of innovation, visit https://global.vrtx.com/ or follow us on Twitter and LinkedIn.

Advertisement. Scroll to continue reading.
Advertisement. Scroll to continue reading.

Special Note Regarding Forward-Looking Statements

This press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, including, without limitation, statements made by Ludovic Fenaux, Senior Vice President, Vertex International, and Professor John Wilson AM, Head, Cystic Fibrosis Service, Alfred Health, in this press release and statements regarding the reimbursement of and access to TRIKAFTA® for certain patients, the estimated number of patients eligible for a CFTR modulator therapy in Australia, including patients that will now have access to a CFTR modulator therapy for the first time, and our beliefs about the benefits of our medicines. While Vertex believes the forward-looking statements contained in this press release are accurate, these forward-looking statements represent the company’s beliefs only as of the date of this press release and there are a number of risks and uncertainties that could cause actual events or results to differ materially from those indicated by such forward-looking statements. Those risks and uncertainties include, among other things, that data from the company’s development programs may not support registration or further development of its compounds due to safety, efficacy, or other reasons, risks related to obtaining approval for and commercializing our medicines, and other risks listed under the heading “Risk Factors” in Vertex’s annual report filed with the Securities and Exchange Commission (SEC) and available through the company’s website at https://global.vrtx.com/ and on the SEC’s website at www.sec.gov. You should not place undue reliance on these statements. Vertex disclaims any obligation to update the information contained in this press release as new information becomes available.

Advertisement. Scroll to continue reading.

(VRTX-GEN)

Contacts

Vertex Pharmaceuticals Incorporated

ADVERTISEMENT

Investors:
Michael Partridge, +1 617-341-6108

or

Manisha Pai, +1 617-429-6891

Media:
mediainfo@vrtx.com
or

International: +44 20 3204 5275

or

U.S.: +1 617-341-6992

Tags: agesAgreementAnnouncesAustraliaCFTRCysticelexacaftortezacaftorivacaftorF508delFibrosisgeneivacaftorMutationolderpatientsReimbursementTRIKAFTAVertexyears
Share196Tweet123Send
ADVERTISEMENT
Previous Post

POINT Biopharma Reports Fiscal 2021 Financial Results and

Next Post

Fogo De Chão Serves Up Next-Level Bar Fogo Experience in

business wire news

business wire news

Business Wire, a Berkshire Hathaway company, is the global leader in press release distribution and regulatory disclosure.

Next Post

Fogo De Chão Serves Up Next-Level Bar Fogo Experience in

  • Trending
  • Comments
  • Latest

GreenCell Mobility Unveils ‘NueGo’ – First Pan-India Intercity Electric Mobility Coach Brand

22/04/2022

Sinch AB (publ) has published its Annual Report for 2021

22/04/2022

HarperCollins Presents THE RESILIENT SOCIETY: Economics After Covid by Markus Brunnermeier

22/04/2022

Mind Wars To Organise Mumbai Debate Championship 2021 : Zee Entertainment

ABP Network celebrated Doctors Day with special programming initiatives

Coca-Cola India appointment Devyani Rajya Laxmi Rana as Vice President of Public Affairs for India and Southwest Asia

Coca-Cola India appointment Devyani Rajya Laxmi Rana as Vice President of Public Affairs for India and Southwest Asia

CGTN: Hong Kong youths embrace brighter future as city integrates into national development

01/07/2022

Mitsubishi Electric Initiates it’s New Factory Automation Systems Manufacturing Facility Groundbreaking in Maharashtra

01/07/2022

Social network Zorro rebrands as Hood ahead of its US launch

01/07/2022
ADVERTISEMENT
ADVERTISEMENT
Life Care News

Copyright © 2015 - 2021 Lifecarenews.in

LIFE CARE IS REGISTERED MAGAZINE IN RNI, NO.GUJGUJ/2015/71283

  • Home
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms of Service
  • Editorial Guidelines

Follow Us

No Result
View All Result
  • Home
  • Business
    • BusinessWire
    • GlobeNewswire
    • Banking
  • News
    • Startups
    • Feature News
    • Energy
    • Real Estate
    • Environment
    • Uncategorized
  • Tech
  • Entertainment
    • Lifestyle
    • Fashion
    • Travel
  • Health
    • Food
  • Education
    • Books
  • Technology
  • Automobile
  • Sports
    • Olympic

Copyright © 2015 - 2021 Lifecarenews.in

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In
Go to mobile version