Successful Completion of First CRS with HIPEC on a 60-year-old Woman with Advanced Peritoneal Carcinomatosis

KOLKATA, India, July 28, 2025 /PRNewswire/ — In a landmark achievement, a 60-year-old woman with advanced primary peritoneal carcinomatosis was successfully treated with Cytoreductive Surgery (CRS) combined with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) at Manipal Hospital Dhakuria, under the expertise of Dr. Ashutosh Daga, Medical Oncologist, and Dr. Sagnik Ray, Surgical Oncologist. The 12-hour long procedure adds a milestone in cancer care treatment.

The sexagenarian was initially taken to another hospital where she was misdiagnosed as a case of chronic liver failure with ascites. When she came to Manipal Hospital Dhakuria, she had trouble breathing and was admitted to the ICU. In the ICU, the fluid in her lungs was drained and chemotherapy was done. Initially, she needed chemotherapy every week but as soon as her condition improvised, she needed it once in three weeks. Subsequently, she was also shifted to the general ward.

“We are proud to announce the successful completion of our first CRS with HIPEC at Manipal Hospital Dhakuria—an emerging center for comprehensive cancer care in Kolkata,” said Dr. Ashutosh Daga. He went on to add, “Although we have previously performed a lot of CRS procedures and managed numerous advanced malignancies in collaboration with our medical oncologists, this was our first CRS case incorporating HIPEC that paves the way for complex procedures at the hospital for cancer patients.“

Cytoreductive Surgery (CRS) combined with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) is a highly specialized and evolving treatment modality used in the management of select gynecological, gastrointestinal, and occasionally thoracic malignancies. This complex procedure demands surgical precision and seamless coordination across multiple departments—including Anesthesiology, Critical Care, Physical Medicine, and Transfusion Medicine.

Dr. Sagnik Ray said, “After 5 months of chemotherapy, she underwent optimal cytoreduction followed by intraoperative delivery of heated chemotherapy using a dedicated HIPEC machine, and she responded to the treatment in a positive manner. The patient had an excellent recovery and was discharged in stable condition on the 9th day of the surgery.” 

About Manipal Hospitals

As a pioneer in healthcare, Manipal Hospitals is among the top healthcare providers in India serving over 7 million patients annually. Its focus is to develop an affordable, high-quality healthcare framework through its multispecialty and tertiary care delivery spectrum and further extend it to out-of-hospital care. With the completion of the acquisition of Medica Synergie hospitals and AMRI Hospitals Limited (acquired in Sept 2023), the integrated network today has a pan-India footprint of 37 hospitals across 19 cities with 10,500+ beds, a talented pool of 5,600+ doctors and an employee strength of over 18,600. Manipal Hospitals provides comprehensive curative and preventive care for a multitude of patients from around the globe. Manipal Hospitals is NABH and AAHRPP accredited, and most of the hospitals in its network are NABL, ER, and Blood Bank accredited and recognized for Nursing Excellence. Manipal Hospitals has also been recognized as the most respected and patient-recommended hospital in India through various consumer surveys.

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